All Articles
Planned Surgery Can Offer Better Long-Term Survival Than Ongoing Medication in Ulcerative Colitis
Is planned surgery safer than ongoing medication for ulcerative colitis? A 25-year nationwide study of 9,200 adults reveals that elective colectomy is associated with lower long-term mortality compared to continuing medical therapy, especially for patients reliant on steroids.
‘Forever Chemicals’ in Daily Life May Weaken Your Gut Shield Years Before IBD
Can everyday forever chemicals trigger IBD? A new $3.3 million Mount Sinai study investigates how PFAS exposure damages the gut’s protective sugar coating up to 10 years before Crohn’s or colitis symptoms appear.
The ‘Exposome’ Framework Is Unlocking the Future of IBD Prevention
Why do environmental exposures matter in IBD? A 2026 Nature Reviews landmark paper introduces the “exposome” framework, revealing how lifetime chemical, dietary, and physical exposures interact with genes to enable IBD prevention.
A Natural Pomegranate Compound Helps Heal the Intestine in IBD
Can pomegranates help heal your gut? A 2026 study in Nature Communications reveals that urolithin A, a compound made by gut bacteria from pomegranates and walnuts, activates a hidden repair pathway that strengthens the intestinal barrier in IBD.
Eating with a J-Pouch: How Smart Dietary Choices Support Your Health After J-Pouch Surgery
How does diet affect life with a J-pouch? A 2026 cross-sectional study in Crohn’s & Colitis 360 reveals how food choices, soluble fibre intake, and antioxidant balance impact bowel function and pouchitis risk after restorative surgery.
Your Feelings About IBD Affect Your Ability to Understand Medical Advice
Why does medical information feel harder to digest during a flare? A 12-month multicentre study of 455 IBD patients reveals that negative illness perceptions directly cause future health literacy difficulties, highlighting the need for integrated psychological support.
Combining Ustekinumab with Liquid Nutrition Boosts Gut Healing in Crohn’s Disease
Can liquid nutrition make biologic drugs work better? A 4-year study of 114 Crohn’s patients reveals that combining ustekinumab with 16 weeks of Exclusive Enteral Nutrition more than doubles gut lining healing rates at week 16 and week 52.
Single Stool Transplant Clears ‘Sticky’ E. coli from the Gut Wall in Crohn’s Disease
Can a stool transplant clear bad bacteria from the gut lining? A 2026 Nature Communications trial of 30 Crohn’s patients shows a single FMT dose completely cleared sticky adherent-invasive E. coli from the intestinal wall in all confirmed carriers.
Mirikizumab Reduces Bowel Urgency and Restores Daily Freedom in Ulcerative Colitis
The 28-week LUCENT-URGE trial of 172 ulcerative colitis patients reveals that mirikizumab reduced urgency severity by 52%, halved daily urgent toilet trips, and tripled stool deferral time.
Trendy vs Proven: What Science Really Says About Popular Diets and IBD Safety
Are trendy popular diets safe for IBD? A comprehensive 2026 scientific review evaluates Mediterranean, low-FODMAP, keto, and structured medical diets, revealing what truly calms symptoms versus what heals gut inflammation.
The Brain-Gut Circuit: How Crohn’s Disease Shifts Neural Networks and Drives Anxiety
How does Crohn’s disease alter your brain? A neuroimaging study of 161 participants reveals that Crohn’s disrupts key brain networks responsible for sensing body signals, showing how anxiety physically changes neural communication between the brain and gut.
Surgery or Biologics First? Early Resection Can Offer Long-Term Drug-Free Remission in Localised Crohn’s Disease
Should surgery be considered earlier for Crohn’s disease? A 2026 meta-analysis of 1,644 patients reveals that early ileocaecal resection reduces the risk of future surgery by 91% and leaves nearly half of patients completely drug-free.
TL1A Inhibitors and Top-Down Therapy Are Changing IBD Care
Can early treatment prevent Crohn’s surgery? A 4.5-year study reveals that starting advanced biologics early reduces surgery risk fivefold, while new TL1A inhibitor tulisokibart delivers high rates of complete disease clearance in ulcerative colitis.
Beyond CRP: How a Blood Test Can Detect Deep Mucosal Healing in Ulcerative Colitis
Can a blood test detect complete gut healing? An 8-year study of 182 ulcerative colitis patients reveals that Serum Amyloid A (SAA) acts as a high-resolution biomarker, successfully differentiating complete mucosal healing from mild residual swelling.
Combining Forces: How Dual Biologic Therapy Offers New Hope for Children with Refractory IBD
Can combining two biologics help children with severe IBD? A 12-month study of 21 paediatric patients reveals that dual biologic therapy (anti-TNF plus vedolizumab) helped 72% achieve clinical remission and significantly boosted gut wall healing.
Probiotics Accelerate Gut Microbiome Recovery Following Bowel Prep & Colonoscopy
How does colonoscopy prep affect your gut bacteria? A 2026 clinical trial of 79 participants reveals that PEG bowel prep temporarily flushes out gut microbes, and taking probiotics for 28 days significantly speeds up microbiome recovery in ulcerative colitis.
Planning for Parenthood: How Smart Medical Strategies Help You Have a Safe, Healthy Pregnancy with IBD
Can you have a safe pregnancy with IBD? Expert guidance from Weill Cornell Medicine reveals why 3 to 6 months of remission, proactive planning, and understanding which medications are safe ensure a healthy pregnancy for women with Crohn’s or colitis.
Ultra-Processed Foods and Crohn’s Relapse: How What You Eat Affects Your Flare-Up Risk
Do packaged foods trigger Crohn’s flares? A 2026 meta-analysis tracking 276 patients in remission reveals that a high intake of ultra-processed foods more than doubles the odds of a clinical relapse within one year.
Temporary Metallic Stents Offer a Safer Way to Treat Crohn’s Bowel Narrowing
Can temporary metal stents open Crohn’s bowel strictures? A new 2026 pilot study of 5 patients tests self-expandable metallic stents left in place for one week, offering a gentler alternative to surgery for scar tissue narrowing.
The Silent Domino: How Hidden Cell-Death Signals Predict IBD Flare-Ups Before Symptoms Return
Why do IBD flares happen during deep remission? A landmark 2-year study in Science reveals a “smouldering” molecular defect where gut cells stay primed to die, opening new doors for early flare prediction and targeted prevention.
How a New Wearable Sensor Tracks IBD Inflammation in Real Time
Can a wearable sensor track gut inflammation through your sweat? A new 2026 study of 33 IBD patients shows that a small, non-invasive skin patch measures CRP and calprotectin continuously, offering a painless alternative to blood and stool tests.
Predicting Repeat Surgery: How a Key Tissue Protein and Smart Calculator Help Protect Your Bowel After Crohn’s Surgery
Can doctors predict if Crohn’s disease will return after surgery? A 2026 study of 280 patients reveals that measuring the integrin αvβ6 tissue protein creates a smart risk calculator to predict surgical recurrence and prevent repeat operations.
How Childhood Exposure to a Sibling with Crohn’s Disease Shapes Your Gut Microbiome
Does growing up with a sibling who has Crohn’s disease change your gut? A 10-year global study reveals that childhood exposure alters key gut bacteria, quadrupling disease risk and opening new doors for early prevention.
How Polydatin Re-balances Gut Immune Cells in Ulcerative Colitis
Can a natural plant compound reset your immune system? A 2026 preclinical study reveals how polydatin unlocks an internal antioxidant pathway (KEAP1-NFE2L2) to reduce inflammatory T cells and protect against ulcerative colitis.
Unlocking the J-Pouch Puzzle: Six Key Risk Factors for Chronic Pouchitis
What drives chronic pouchitis after J-pouch surgery? A major 2026 meta-analysis of over 4,200 ulcerative colitis patients identifies six key risk factors, from smoking and liver conditions to extraintestinal symptoms, helping you and your care team plan safer post-surgery care.
Strategies for Managing IBD When Treatment Options Seem Limited
What happens when standard IBD drugs stop working? Experts at the 2026 Crohn’s & Colitis Congress reveal why refractory disease requires checking for scar tissue, exploring combination therapies, and fixing hidden stoma complications.
How AI is Unlocking Early Intestinal Fibrosis Crohn’s Care
Can artificial intelligence prevent Crohn’s disease surgery? A new 2026 study uses generative AI to map 43 key genes and gut bacteria shifts linked to bowel scarring, opening the door for early diagnostic tests and anti-scarring treatments.
How Whole Foods Can Help Heal Your Gut in IBD
How does what you eat impact your IBD? A landmark 2026 review in BMJ Gut reveals how ultra-processed Western foods fuel gut inflammation, and why moving toward fresh, whole foods and Mediterranean-style eating offers a proven way to support deep healing.
Tofacitinib: When ‘Less is More’ on Your Ulcerative Colitis Journey
Can you safely lower your ulcerative colitis dose? The long-term follow-up of the randomized RIVETING trial reveals that 50% of patients successfully maintained remission on a reduced dose of tofacitinib, while those who relapsed safely recaptured remission by stepping their dose back up.
How Your Body Size History and Genes Cooperate to Shape Your Ulcerative Colitis Risk
Does your childhood weight history affect your adult gut? A massive 15-year study of over 260,000 people reveals how your physical growth trajectory and your “genetic scorecard” combine to influence your risk of adult-onset ulcerative colitis.
